Publications
Chambers RA, Toombs C: Deep Network Pharmacology: Targeting Glutamate Systems as Integrative Treatments for Jump-Starting Neural Networks and Recovery Trajectories. J Psychiatry Brain Sci. 2021;6:e210008.
The neural basis of addiction: a pathology of motivation and choice – PubMed (nih.gov)
Kalivas PW, Volkow ND. The neural basis of addiction: a pathology of motivation and choice. Am J Psychiatry. 2005 Aug;162(8):1403-13. doi: 10.1176/appi.ajp.162.8.1403. PMID: 16055761.
Niedzielska-Andres E, Pomierny-Chamioło L, Andres M, Walczak M, Knackstedt LA, Filip M, Przegaliński E. Cocaine use disorder: A look at metabotropic glutamate receptors and glutamate transporters. Pharmacol Ther. 2021 May;221:107797. doi: 10.1016/j.pharmthera.2020.107797. Epub 2021 Jan 9. PMID: 33359590.
Rasmussen K, White DA, Acri JB. NIDA’s medication development priorities in response to the Opioid Crisis: ten most wanted. Neuropsychopharmacology. 2019 Mar;44(4):657-659. doi: 10.1038/s41386-018-0292-5. Epub 2018 Dec 7. PMID: 30538289; PMCID: PMC6372702.
Rasmussen K, Kendrick WT, Kogan JH, Aghajanian GK. A selective AMPA antagonist, LY293558, suppresses morphine withdrawal-induced activation of locus coeruleus neurons and behavioral signs of morphine withdrawal. Neuropsychopharmacology. 1996 Nov;15(5):497-505. doi: 10.1016/S0893-133X(96)00094-2. PMID: 8914123.
Sang CN, Hostetter MP, Gracely RH, Chappell AS, Schoepp DD, Lee G, Whitcup S, Caruso R, Max MB. AMPA/kainate antagonist LY293558 reduces capsaicin-evoked hyperalgesia but not pain in normal skin in humans. Anesthesiology. 1998 Nov;89(5):1060-7. doi: 10.1097/00000542-199811000-00005. PMID: 9821993.
Sang CN, Ramadan NM, Wallihan RG, Chappell AS, Freitag FG, Smith TR, Silberstein SD, Johnson KW, Phebus LA, Bleakman D, Ornstein PL, Arnold B, Tepper SJ, Vandenhende F. LY293558, a novel AMPA/GluR5 antagonist, is efficacious and well-tolerated in acute migraine. Cephalalgia. 2004 Jul;24(7):596-602. doi: 10.1111/j.1468-2982.2004.00723.x. PMID: 15196302.